Possibilistic Channels for DNA Word Design

We deal with DNA combinatorial code constructions, as found in the literature, taking the point of view of possibilistic information theory and possibilistic coding theory. The possibilistic framework allows one to tackle an intriguing information-theoretic question: what is channel noise in molecular computation? We examine in detail two representative DNA string distances used for DNA code constructions and point out the merits of the first and the demerits of the second. The two string distances are based on the reverse Hamming distance as required to account for hybridisation of DNA strings.